Small Molecule Inhibitors of a Common Conformational Morphology Identified in Intrinsically Disordered Proteins

Time: 9:00 am
day: Day One

Details:

  • Common Conformational Morphology (CCM) acts as an in silico crystal structure  for IDPs
  • Hit identification has been performed for alpha synuclein, amylin, amyloid beta, and tau
  • Demonstrated dose dependent decrease in oligomeric species of amyloid beta and tau 

Speakers: